Author

Alexandra Lucienne Fox

Wayne State UniversityORCID 0000-0002-7728-4270Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 4 Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Ayesha B. AlveroiD· 4 shared Gil MoriD· 4 shared Radhika P. GogoiiD· 3 shared Hussein ChehadeiD· 2 shared Michael ChoppiD· 2 shared Michael Millman· 2 shared Nicholas K. AdzibolosuiD· 2 shared Roslyn TedjaiD· 2 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersCancer Biology

Ayesha B. AlveroORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Cancer BiologyMolecular OncologyPeer-reviewedFeb 13, 2026

Engineered Extracellular Vesicles Enriched with the miR-214/199a Cluster Enhance the Efficacy of Chemotherapy for Ovarian Cancer

Weida Wang, Ayesha B. Alvero, Yi Qin…·Yi Zhang

This paper shows engineered extracellular vesicles carrying miR-214-3p/miR-199a-5p enhance chemotherapy effectiveness in ovarian cancer by reversing chemoresistance and reprogramming tumor EV communication.

2 citations

mouseexperimental assay

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Cancer BiologyFrontiers in OncologyPeer-reviewedJul 22, 2024

Adipose microenvironment promotes hypersialylation of ovarian cancer cells

Alexandra Lucienne Fox, Garry D. Leonard, Nicholas K. Adzibolosu…·Ayesha B. Alvero

This study shows that the adipose microenvironment increases sialylation in ovarian cancer cells, promoting tumor growth in immune-dependent settings.

7 citations

humanmouse

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ImmunologyCancer Immunology ResearchPeer-reviewedDec 11, 2023

Immune modulation of innate and adaptive responses restores immune surveillance and establishes anti-tumor immunological memory

Ayesha B. Alvero, Alexandra Lucienne Fox, Bhaskara Reddy Madina…·Gil Mor

This paper develops CARG-2020, a virus-like-vesicle that modulates immune responses to enhance anti-tumor immunity and establish immunological memory in ovarian cancer.

15 citations

mouseexperimental assay

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Cancer BiologyJournal of Ovarian ResearchPeer-reviewedNov 30, 2023

Adipose-derived exosomal miR-421 targets CBX7 and promotes metastatic potential in ovarian cancer cells

Yi Zhang, Roslyn Tedja, Michael Millman…·Ayesha B. Alvero

This study identifies adipose-derived exosomal miR-421 as a regulator of CBX7 expression, promoting ovarian cancer metastasis by inducing epigenetic changes.

15 citations

humanexperimental assay

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