Zhen Li

Live imaging reveals oocyte membrane pre-remodeling forming permissive space for asymmetric division

The paper uses live imaging to show that mouse oocytes undergo membrane remodeling to create a pre-extrusion space for polar body extrusion, regulated by ERK-ZO-1 signaling.

WTAP-mediated epitranscriptomic program in alveolar macrophages confers prolonged protection against postinfluenza bacterial pneumonia

The paper shows that reduced m6A in alveolar macrophages after influenza enhances trained immunity, improving antibacterial function and protecting against secondary infections.

A global metagenomic atlas uncovers ubiquitous biosynthetic potential linked to adaptation in extreme environments

The paper constructs a global metagenomic atlas of extremophilic microbes, revealing habitat-specific biosynthetic potential linked to adaptation in extreme environments.

The BELL-type homeobox transcription factor RLC3/OsBLH4 controls leaf rolling and drought tolerance via KNOX-BELL-lignin regulatory network in rice

Bergeyella cardium variant induces unique cytoplasmic vacuolization cell death

This study identifies Bergeyella cardium variant-induced cytoplasmic vacuolization cell death and shows SLC9A9 and OMVs play key roles in this process.

Single-dose rapamycin increases brain glucose metabolism but reduces synaptic density in Long-Evans rats

This study examines the effects of a single rapamycin dose on brain glucose metabolism and synaptic density in rats using PET imaging, finding increased metabolism and decreased synaptic density.

Multipath projection stereolithography (MPS) for 3D printing microfluidic devices

The paper introduces MPS, a 3D printing method for microfluidic devices, enabling high-resolution features on centimeter-sized constructs.

collectNET: a web server for integrated inference of cell-cell communication network

collectNET infers cell-cell communication networks using three methods and provides an online tool with visualization and a human communication atlas.

Seamless Multiscale Modeling of Coagulation Using Dissipative Particle Dynamics

This paper introduces a multiscale modeling framework for blood clotting that integrates blood rheology, cell mechanics, coagulation kinetics, and transport dynamics, showing the impact of flow on thrombus formation.