Molecular BiologyOxidative Medicine and Cellular LongevityPeer-reviewed
Synergism and antagonism of two distinct, but confused, Nrf1 factors in integral regulation of the nuclear-to mitochondrial respiratory and antioxidant transcription networks
Shuwei Zhang, Yangxu Deng, Yuancai Xiang…·Yiguo Zhang
The paper identifies synergistic and antagonistic roles of Nfe2l1 and Nfe2l2 in regulating -PalNRF1 and TFAM expression, with species-specific differences observed between mice and humans.