Molecular BiologyPLoS PathogensPeer-reviewed
Post-infection treatment with the E protein inhibitor BIT225 reduces disease severity and increases survival of k18-hACE2 transgenic mice infected with a lethal dose of SARS-CoV-2
Gary D. Ewart, Michael D. Bobardt, Bo Hjorth Bentzen…·Philippe A. Gallay
This paper shows that BIT225, an E-protein inhibitor, reduces disease severity and increases survival in SARS-CoV-2 infected mice when administered before or after infection.
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