Synthetic BiologybioRxivPreprint
PepRePs: Peptide-Retargeted Phosphatases Designed with Generative Language Models
Lauren Hong, Tai-Chen Ho, Yi-Shiuan Tseng…·Pranam Chatterjee
This paper introduces PepRePs, a system using peptide-retargeted phosphatases to selectively manipulate protein phosphorylation, showing reduced phosphorylation and downstream effects on cellular processes.
DOI 10.64898/2026.10.05.756719