Po‐Han Chen

This paper introduces PepRePs, a system using peptide-retargeted phosphatases to selectively manipulate protein phosphorylation, showing reduced phosphorylation and downstream effects on cellular processes.

This study demonstrates that MET-targeting VHH-CAR-T cells effectively kill tumor cells in vitro and control tumor growth in vivo.

This study uses optogenetics to show that unilateral inhibition and excitation of basal ganglia output to motor thalamus in mice oppositely affect directional licking choices and movement initiation.

This study identifies O-GlcNAcylation of gigaxonin as a regulatory mechanism linking metabolism to intermediate filament proteostasis, offering insights into giant axonal neuropathy.