BiochemistrybioRxivPreprint
A split crRNA with CRISPR-Cas12a enables highly sensitive, selective, and multiplexed detection of RNA and DNA
Jie Qiao, Yichuan Chen, Xinping Wang…·Yi Liu
This paper develops a split CRISPR-Cas12a system for sensitive, selective, and multiplexed detection of RNA and DNA without reverse transcription, achieving low detection limits and improved specificity.
DOI 10.1101/2024.01.04.574169