Author

Yihan Chen

Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

Abhijit ParoliaiD· 1 shared Allison Rose HanafordiD· 1 shared Alvin Huang· 1 shared Anastasia Dimitriou· 1 shared Angela Zhang· 1 shared Arul M. ChinnaiyaniD· 1 shared Ashley Ching· 1 shared Brittany M. JohnsoniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Abhijit ParoliaORCID

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2 papers

Recent·Most cited

Single-Atom Modification Enables Reversal of Degradation Selectivity between NSD2 and GSPT1

Weizhong Shen, Yihan Liu, Lianchao Liu, Yingfan Liu, Yan Zhang, Yihan Chen, Lei Wang, Zhiyi Zhou, Angela Zhang, Hui Shen, Fengtao Zhou, Weixue Huang, Xiaomei Ren, Abhijit Parolia, Yong Xu, , Ke Ding

This study modifies a molecule to create two variants with different target selectivity, showing how small structural changes can control degradation activity.

Journal of Medicinal Chemistry · Oct 4, 2026Peer-reviewedCancer Biology

MyD88 deficiency modestly attenuates disease in a Leigh syndrome mouse model while enrofloxacin accelerates disease

Allison Rose Hanaford, Elizaveta A. Olkhova, Ryan W. Liao, Ashley Ching, Alvin Huang, Erin Shien Hsieh, Kino Watanabe, Yihan Chen, Megan Wichman, Noelle Hwang, Katerina James, Michael T. Mulholland, Vivian Truong, Holly Coulson, Kerry Gibbins, , Simon C. Johnson

The paper investigates the role of TLR signaling in Leigh syndrome using a mouse model and finds that MyD88 deficiency modestly improves disease outcomes, while enrofloxacin treatment accelerates disease progression.

Journal of Neuropathology & Experimental Neurology · Sep 4, 2026Peer-reviewedNeuroscience