ImmunologyImmunityPeer-reviewed
Cryo-EM structural insights into Vγ9Vδ2 TCR activation via multiple butyrophilins
Mai Zhang, Yiqing Wang, Ningning Cai…·Yonghui Zhang
This paper presents cryo-EM structures of BTN proteins interacting with phosphoantigens and the Vγ9Vδ2 TCR, revealing a 'pliers-like gripping' mechanism for TCR activation.