NeuroscienceMolecular TherapyPeer-reviewed
APOE2 gene therapy reduces amyloid deposition, and improves markers of neuroinflammation and neurodegeneration in a mouse model of Alzheimer disease
Rosemary J. Jackson, Megan S. Keiser, Jonah C Meltzer…·Bradley T. Hyman
This paper shows that APOE2 gene therapy reduces amyloid deposition, neurodegeneration, and microglial activation in an Alzheimer's mouse model with ongoing APOE4 expression.
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