Crosstalk Among Disrupted Blood-Brain Barrier, Neuroinflammation, and Coagulopathy in AC70 hACE2 Tg Mice with Prolonged Neurological Manifestations Induced by the Omicron BA.1 Variant of SARS-CoV-2
Aleksandra K. Drelich, Panatda Saenkham, Yu-Hsiu Wang, Xuping Xie, Barbara M. Judy, Thomas G. Ksiazek, Bi‐Hung Peng, Chien-Te Kent Tseng
This study investigates prolonged neurological effects in AC70 hACE2 Tg mice infected with Omicron BA.1, showing BBB disruption, neuroinflammation, and coagulopathy contribute to long-COVID-like symptoms.
bioRxiv · Apr 3, 2025 · PreprintMicrobiology