Bi‐Hung Peng

This study develops VSA-2, a plant-derived adjuvant for SARS-CoV-2 subunit vaccines, showing it induces strong immune responses and protection comparable to QS-21.

This study investigates prolonged neurological effects in AC70 hACE2 Tg mice infected with Omicron BA.1, showing BBB disruption, neuroinflammation, and coagulopathy contribute to long-COVID-like symptoms.

This study investigates SARS-CoV-2 neuroinvasion via the trigeminal nerve in AC70 human ACE2 transgenic mice, finding it as an efficient route with altered neuronal function and gene expression but limited tissue pathology.

This study characterizes the coagulopathy in AC70 hACE2 transgenic mice infected with SARS-CoV-2, revealing hypercoagulable states and ANXA2 system dysregulation.

This study uses a murine model to investigate persistent neurological symptoms after SARS-CoV-2 Delta variant infection, finding long-term immune activation and behavioral abnormalities.

The paper designs a new class of protease inhibitors targeting coronavirus Mpro, identifying ML1000 as a potent inhibitor with low-nanomolar affinity and antiviral activity.