Author

Thomas G. Ksiazek

The University of Texas Medical Branch at GalvestonORCID 0000-0003-4160-8218Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:variant calling· 1 Organism:virus· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Barbara M. JudyiD· 3 shared Aleksandra K. DrelichiD· 2 shared Bi‐Hung PengiD· 2 shared Chien-Te Kent TsengiD· 2 shared Panatda SaenkhamiD· 2 shared Aaron L. MilleriD· 1 shared Allan McConnell· 1 shared Andrew L. RouthiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMicrobiology

Barbara M. JudyORCID

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Author profile →

3 papers

Recent·Most cited

MicrobiologybioRxivPreprintApr 3, 2025

Crosstalk Among Disrupted Blood-Brain Barrier, Neuroinflammation, and Coagulopathy in AC70 hACE2 Tg Mice with Prolonged Neurological Manifestations Induced by the Omicron BA.1 Variant of SARS-CoV-2

Aleksandra K. Drelich, Panatda Saenkham, Yu-Hsiu Wang…·Chien-Te Kent Tseng

This study investigates prolonged neurological effects in AC70 hACE2 Tg mice infected with Omicron BA.1, showing BBB disruption, neuroinflammation, and coagulopathy contribute to long-COVID-like symptoms.

DOI 10.1101/2025.04.03.646981

mouseexperimental assay

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MicrobiologyPLoS PathogensPeer-reviewedJun 24, 2024

Characterization of Unique Pathological Features of COVID-Associated Coagulopathy: Studies with AC70 hACE2 Transgenic Mice Highly Permissive to SARS-CoV-2 Infection

Aleksandra K. Drelich, Kempaiah Rayavara, Jason C. Hsu…·Chien-Te Kent Tseng

This study characterizes the coagulopathy in AC70 hACE2 transgenic mice infected with SARS-CoV-2, revealing hypercoagulable states and ANXA2 system dysregulation.

10 citations

mouseexperimental assay

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Molecular BiologyeLifePeer-reviewedSep 28, 2021

Tiled-ClickSeq for targeted sequencing of complete coronavirus genomes with simultaneous capture of RNA recombination and minority variants

Elizabeth A. Jaworski, Rose M. Langsjoen, Brooke M. Mitchell…·Andrew L. Routh

Tiled-ClickSeq enables complete SARS-CoV-2 genome sequencing with detection of RNA recombination and minority variants in a single assay.

27 citations

viruswhole-genome sequencing

𝕏 PostBluesky