Cancer BiologybioRxivPreprint
Cell context-specific Synthetic lethality Prediction and Mechanism Analysis
Yucui Xing, Mengchen Pu, Kaiyang Cheng…·Yingsheng Zhang
This paper introduces SLWise, a deep-learning model for predicting synthetic lethal interactions in specific cellular contexts, and SLAD-CE for analyzing their mechanisms, showing improved accuracy over existing methods.
DOI 10.1101/2023.09.13.557545