Cancer BiologyCell ReportsPeer-reviewed
Metabolic reinvigoration of NK cells by IL-21 enhances immunotherapy against MHC-I deficient solid tumors
Yi Wang, Chao Huang, Guoxin Cai…·Li Tang
This paper shows that IL-21-Fc reprograms NK cell metabolism to enhance their function against MHC-I deficient tumors, leading to tumor eradication in preclinical models.
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