Cell BiologyNucleic Acids ResearchPeer-reviewed
Ribosome Quality Control Mechanism Mitigates the Cytotoxic Impacts of Ribosome Collisions Induced by 5-Fluorouracil
Susanta Chatterjee, Parisa Naeli, Okan Onar…·Seyed Mehdi Jafarnejad
This study shows that 5-Fluorouracil induces ribosome collisions, which are mitigated by the RQC mechanism through mTOR-dependent regulation of RQC factors.
18 citations