Author

John R. P. Knight

University of ManchesterORCID 0000-0002-8771-5484Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Kexin Dang· 2 shared Mark P. SaundersiD· 2 shared Nicole Simms· 2 shared Aitor GarziaiD· 1 shared Angela P. Hackett· 1 shared Aynur Soenmez· 1 shared Callum David Holmes· 1 shared Christos G. GkogkasiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMolecular Biology

Kexin Dang

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintApr 1, 2025

AquIRE reveals multiple mechanisms of clinically induced RNA damage and the conservation and dynamics of glycoRNAs

Zijian Zhang, Zornitsa Vasileva Kotopanova, Kexin Dang…·John R. P. Knight

The paper develops AquIRE to quantify RNA damage and identifies multiple mechanisms of clinically induced RNA modifications, including glycoRNA dynamics across life kingdoms.

2 citations

experimental assay

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Cell BiologyNucleic Acids ResearchPeer-reviewedSep 17, 2024

Ribosome Quality Control Mechanism Mitigates the Cytotoxic Impacts of Ribosome Collisions Induced by 5-Fluorouracil

Susanta Chatterjee, Parisa Naeli, Okan Onar…·Seyed Mehdi Jafarnejad

This study shows that 5-Fluorouracil induces ribosome collisions, which are mitigated by the RQC mechanism through mTOR-dependent regulation of RQC factors.

18 citations

humanmetabolomics

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