Disturbing immune homeostasis by neutrophil loss of Uba1 induces VEXAS-like autoinflammatory disease in mice
Ge Dong, Jingjing Liu, Hongxi Zhou…·Zhigang Cai
This study shows that neutrophil loss of Uba1 in mice causes VEXAS-like autoinflammatory disease, with symptoms including increased neutrophils, cytokines, and vacuoles.