PathologybioRxivPreprint
Pharmacological activation of mitophagy prevents calcific aortic valve disease by targeting dysregulated mitochondrial-to-nuclear communication
Dao Zhou, Hanyi Dai, Junhao Qiu…·Xianbao Liu
This study shows that activating mitophagy with TJ0113 prevents calcific aortic valve disease by restoring mitochondrial-to-nuclear communication disrupted in diseased valves.