Yvonne Woitzat

The paper shows that Aβ and mutant Tau reduce neuronal activity in young C. elegans before amyloid aggregation, with muscle-expressed Aβ affecting neurons via retrograde signaling.

This study shows UVB exposure mimics dietary restriction by altering mitochondrial bioenergetics in C. elegans and human cells, triggering metabolic re-wiring and requiring mitochondrial fusion for recovery.