Author

Z. Herbert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Chakraborty· 1 shared A. Creech· 1 shared A. J. Dafferner· 1 shared A. Ringel· 1 shared B. A. Teply· 1 shared B. Olenchock· 1 shared C. Morrissey· 1 shared D. Costanzo-Garvey· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. Chakraborty

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Author profile →

2 papers

Recent·Most cited

Androgen-mediated TGFβ expression suppresses anti-tumor neutrophil response in bone metastatic prostate cancer

M. Alsamraae, D. Costanzo-Garvey, B. A. Teply, S. Boyle, G. Sommerville, Z. Herbert, C. Morrissey, A. J. Dafferner, M. Y. Abdalla, R. W. Fallet, T. Kielian, H. Jensen-Smith, E. I. deOliveira, K. Chen, I. A. Bettencourt, , L. M. Cook

This study identifies androgen-mediated TGFβ expression as a mechanism suppressing anti-tumor neutrophil response in bone metastatic prostate cancer and shows that combining ADT with TGFβ receptor inhibition restores neutrophil cytotoxicity.

bioRxiv · Dec 30, 2022 · PreprintCancer Biology

The UTX Tumor Suppressor Directly Senses Oxygen to Control Chromatin and Cell Fate

A. Chakraborty, T. Laukka, M. Myllykoski, A. Ringel, M. Booker, M. Tolstorukov, Y. Meng, S. Meier, R. Jennings, A. Creech, Z. Herbert, J. Spinelli, S. McBrayer, B. Olenchock, J. Jaffe, , W. G. Kaelin

The paper shows that KDM6A, an H3K27 histone demethylase, is oxygen-sensitive and its inactivation under hypoxia affects chromatin and cell fate.

bioRxiv · Jan 3, 2019 · PreprintBiochemistry