ImmunologybioRxiv
Adrenergic signaling in muscularis macrophages limits neuronal death following enteric infection
F. Matheis, P. A. Muller, C. L. Graves…·D. Mucida
The paper investigates how enteric infections affect enteric neurons and shows that intestinal muscularis macrophages use β2-adrenergic receptor signaling to protect neurons via an arginase 1-polyamine axis.
DOI 10.1016/j.cell.2019.12.002