BiophysicsbioRxiv
Spatial and temporal organization of RecA in the Escherichia coli DNA-damage response
H. Ghodke, B. Paudel, J. S. Lewis…·A. M. van Oijen
This study uses a fluorescent probe to track RecA dynamics in live E. coli, showing it is stored during normal metabolism and rapidly mobilizes to form SOS-signaling complexes upon DNA damage.
DOI 10.7554/elife.42761