Author

K. Gopal

Primary ORCID profile (0000-0002-8305-8384 · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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K. GopaliD2 papers · University of Michigan

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1

Frequent Co-Authors

A. A. Greenwell· 1 shared A. M. Abdualkader· 1 shared A. M. Darwesh· 1 shared A. M. van Oijen· 1 shared B. Paudel· 1 shared C. Saed· 1 shared E. A. Wood· 1 shared F. Eaton· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

A. A. Greenwell

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2 papers

Recent·Most cited

Loss of Skeletal Muscle Pyruvate Dehydrogenase Induces Lactic Acidosis and Adaptive Anaplerotic Compensation via Pyruvate-Alanine Cycling and Glutaminolysis

K. Gopal, A. M. Abdualkader, X. Li, A. A. Greenwell, Q. G. Karwi, C. Saed, G. M. Uddin, A. M. Darwesh, K. L. Jamieson, T. R. Altamimi, R. Kim, F. Eaton, J. M. Seubert, G. D. Lopaschuk, J. R. Ussher, R. Al Batran

This study shows that loss of skeletal muscle pyruvate dehydrogenase causes lactic acidosis and early death, but high-fat diets can mitigate these effects.

bioRxiv · May 10, 2023 · PreprintCell Biology

Spatial and temporal organization of RecA in the Escherichia coli DNA-damage response

H. Ghodke, B. Paudel, J. S. Lewis, S. Jergic, K. Gopal, Z. J. Romero, E. A. Wood, R. Woodgate, M. M. Cox, A. M. van Oijen

This study uses a fluorescent probe to track RecA dynamics in live E. coli, showing it is stored during normal metabolism and rapidly mobilizes to form SOS-signaling complexes upon DNA damage.

bioRxiv · Sep 10, 2018Biophysics