Integrated histopathology, spatial and single cell transcriptomics resolve cellular drivers of early and late alveolar damage in COVID-19
J. T. H. Lee, S. N. Barnett, K. Roberts, H. Ashwin, L. Milross, J.-W. Cho, A. Huseynov, B. Woodhams, A. Aivazidis, T. Li, J. Majo, P. C. Guerrero, M. Lee, A. M. A. Miranda, Z. Jablonska, , O. A. Bayraktar
This study integrates single-cell and spatial transcriptomics with histopathology to identify cellular and molecular changes in lung alveolar damage during COVID-19 progression.
bioRxiv · Dec 20, 2023Pathology