Developmental BiologybioRxivPreprint
T-regulatory cell protection of progenitor cells from CD4+ T-cell-mediated cytotoxicity is essential for endogenous mouse digit-tip regeneration.
Zachery Beal, Robyn E. Reeve, Elizabeth Hammond…·James W. Godwin
The paper shows CD4+ T cells inhibit digit-tip regeneration by attacking progenitor cells, which can be counteracted by T regulatory cells or RANKL.
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