Zhuanfen Cheng

The paper creates a tandem repeat atlas for 39 inbred mouse strains using long-read sequencing, showing TRs are abundant but differ from human TRs in expansion and transposable element association.

This study uses an AI co-scientist to identify and validate anti-fibrotic drugs in human hepatic organoids, finding that epigenomic modifiers play a key role in liver fibrosis.

The paper creates a database of structural variants in 40 inbred mouse strains and identifies an SV linked to lymphoma susceptibility in SJL mice.

This study uses a large language model to analyze gene-phenotype relationships in mouse genetic models, identifying causative genetic factors and generating novel hypotheses for spontaneous hearing loss.

This study identifies Nav1 as a gene regulating learning, memory, and responses to addictive drugs through synaptic balance changes in the cortex and hippocampus.

The paper analyzes structural variation in inbred mouse strains to identify genetic factors associated with autism-related traits.

The paper identifies a recurrent tumor-specific transcript fusion between CDKN1A and RAB44 caused by splice-site mutations and shows its correlation with TP53 inactivation and CDK activation.