ImmunologybioRxivPreprint
A novel model demonstrating that human immune cells promote multiorgan SARS-CoV-2 dissemination and human T cells limit anti-viral innate immunity
Amber N. Wolabaugh, Vrushali V. Agashe, Zicheng Wang…·Megan Sykes
This paper develops a human immune system mouse model to study SARS-CoV-2 dissemination and immune responses, finding that human T cells suppress innate immunity and allow viral persistence.