Systems BiologyDisease Models & MechanismsPeer-reviewed
Integrative analysis of Paneth cell proteomic and transcriptomic data from intestinal organoids reveals functional processes dependent on autophagy
Emily J. Jones, Zoe J. Matthews, Lejla Gul…·Tamas Douglas Korcsmaros
The paper integrates proteomic and transcriptomic data from intestinal organoids to identify autophagy-dependent processes in Paneth cells, showing that autophagy impairment affects protein abundance and key cellular functions.
25 citations