Wolfgang Baehr

This study evaluates AAV gene therapy in BCM mouse models, finding that older mutant mice show reduced treatment efficacy due to decreased transduction and cone degeneration, while specific promoters remain active.

This study shows that NUDC is essential for rod photoreceptor function, survival, and maintenance, with loss leading to cell death, protein mislocalization, and retinal degeneration.

This study investigates the role of CEP164 in photoreceptor cilia formation and function by deleting it at different developmental stages in mice, showing that CEP164 is critical for IFT-B recruitment and ciliary maintenance.