Author

Niek F. H. N. van Bree

Karolinska InstitutetORCID 0000-0001-5010-3524Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Leilei ZhouiD· 2 shared Lola BoutiniD· 2 shared Margareta WilhelmiD· 2 shared Ann-Sophie OppeltiD· 1 shared Anna FalkiD· 1 shared Beth CoyleiD· 1 shared Fredrik J. SwartlingiD· 1 shared Jinhye Ryu· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Leilei ZhouORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cancer BiologyNeuro-OncologyPeer-reviewedOct 8, 2024

Development of an orthotopic medulloblastoma zebrafish model for rapid drug testing.

Niek F. H. N. van Bree, Ann-Sophie Oppelt, Susanne Lindström…·Margareta Wilhelm

This paper develops a zebrafish model for medulloblastoma drug testing, showing that neural stem cell culture conditions enhance tumor cell homing and aggressiveness, enabling high-throughput screening.

16 citations

zebrafishbulk RNA-seq

𝕏 PostBluesky

Cancer BiologyNeuro-OncologyPeer-reviewedJun 10, 2024

High-throughput neural stem cell-based drug screening identifies S6K1 inhibition as a selective vulnerability in SHH-medulloblastoma

Leilei Zhou, Niek F. H. N. van Bree, Lola Boutin…·Margareta Wilhelm

7 citations

humanorganoid / primary culture

𝕏 PostBluesky