Author

Dachan Kim

Boston Children's HospitalORCID 0000-0001-5196-8482Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:scRNA-seq· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

August Yue HuangiD· 1 shared Boxun ZhaoiD· 1 shared Brian H. ChhoukiD· 1 shared Christopher A. WalshiD· 1 shared David Alan BennettiD· 1 shared Ed S. LeiniD· 1 shared Edward Stronge· 1 shared Eitan S KaplaniD· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenomics

August Yue HuangORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintJan 3, 2024

Somatic cancer driver mutations are enriched and associated with inflammatory states in Alzheimer's disease microglia

August Yue Huang, Zinan Zhou, Maya Talukdar…·Christopher A. Walsh

The paper identifies somatic driver mutations in microglia of Alzheimer's disease brains, showing increased clonal expansion and inflammatory signatures.

16 citations

humanbulk RNA-seq

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GenomicsbioRxivPreprintAug 23, 2017

Accurate detection of low-level somatic mutations with technical replication for next-generation sequencing

Junho Kim, Dachan Kim, Jae Seok Lim…·Sangwoo Kim

RePlow improves low-VAF somatic mutation detection by using technical replicates, reducing false positives by up to 99%.

1 citation

whole-genome sequencingstatistical model

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