Author

Robert J. Wiener

Icahn School of Medicine at Mount SinaiORCID 0000-0001-5238-1659Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

Hongyan ZouiD· 2 shared Kevin D. CostaiD· 2 shared Rodrigo Alves DiasiD· 2 shared Roland H. FriedeliD· 2 shared Theodore C. HannahiD· 2 shared Aarthi RamakrishnaniD· 1 shared Alexandre WojcinskiiD· 1 shared Angela Dixon· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

Hongyan ZouORCID

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3 papers

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedJan 2, 2025

Invasion of glioma cells through confined space requires membrane tension regulation and mechano-electrical coupling via Plexin-B2

Jade Chan, Theodore Hannah, Sita Sadia…·Roland H. Friedel

This study shows GBM cells use Plexin-B2 to regulate membrane tension and mechano-electrical coupling for migration through confined spaces.

19 citationstop 3%

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BiophysicsbioRxivPreprintOct 3, 2023

Intrinsic Mechanics of Human Stem Cell Derived Aortic Smooth Muscle Cells Support a Developmental Basis for Aneurysm Localization in Marfan Syndrome

Robert J. Wiener, Helen Orins, Kevin D. Costa

This study investigates how intrinsic mechanobiological properties of aortic smooth muscle cells from Marfan Syndrome patients contribute to aneurysm localization in the ascending aorta.

2 citations

humanproteomics

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Developmental BiologyNature CommunicationsPeer-reviewedOct 14, 2021

Plexin-B2 is a key regulator of cell mechanics during multicellular organization

Chrystian Junqueira Alves, Rafael Dariolli, Jonathan C. Haydak…·Roland H. Friedel

This study identifies Plexin-B2 as a regulator of cell mechanics during multicellular organization, showing its role in modulating cell stiffness, contractility, and differentiation in human stem and progenitor cells.

55 citations

humanexperimental assay

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