Peter J O’Toole

This study compares FCS and FRAP techniques to measure diffusion in yeast plasma membrane proteins, revealing discrepancies in Sso2 diffusion due to subdomain localization.

A 3D-printed OpenFlexure Microscope adapted for humid incubators, with relocated electronics, ASA printing and 22 Ω current-limiting resistors, records 48-hour label-free docetaxel responses that CellPhe can analyse.

The paper uses multimodal imaging and single-cell transcriptomics to identify LPCAT2-mediated membrane remodeling in granuloma macrophages during visceral leishmaniasis.

This study uses live-cell imaging and automated phenotyping to characterize cancer-stromal interactions, revealing phenotypic changes in breast cancer cells exposed to cancer-associated fibroblasts.

This study uses high-resolution live cell imaging to characterize sub-cellular structures and dynamic processes in the halotolerant yeast Debaryomyces hansenii, providing a template for studying genetically recalcitrant organisms.