Author

Lapo Mughini‐Gras

Utrecht UniversityORCID 0000-0001-5420-949XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioinformatics· 1 Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 3 Assay:whole-genome sequencing· 3 Organism:E. coli· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Aldert ZomeriD· 2 shared Eelco FranziD· 2 shared Timothy J. DallmaniD· 2 shared Ana AmaroiD· 1 shared Andra Neefjes‐BorstiD· 1 shared Angela H. A. M. van HoekiD· 1 shared Ângela PistaiD· 1 shared Angela van Hoek· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioinformatics

Aldert ZomerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BioinformaticsGenomicsPeer-reviewedAug 23, 2026

Exploring differences across pangenome-graph representations using Escherichia coli O157:H7 as a model

Peilin Liu, Kaixin Hu, Lapo Mughini‐Gras…·Julián Paganini

The paper benchmarks pangenome graph construction methods using Escherichia coli O157:H7 genomes, showing that representation strategies and assembly completeness significantly affect graph topology and accuracy.

DOI 10.1016/j.ygeno.2026.111309

E. coliwhole-genome sequencing

𝕏 PostBluesky

GenomicsbioRxivPreprintApr 28, 2026

Population analysis and host-disease associations of Shiga toxin-producing Escherichia coli from various sources across eleven European countries using whole genome sequencing

Rosangela Tozzoli, Tristan Schadron, Arnold Knijn…·Camilla Sekse

This paper analyzes STEC population structure and host-disease associations using whole genome sequencing of 3,418 isolates from 11 European countries, identifying distinct subpopulations linked to disease severity.

DOI 10.64898/2026.04.27.721056

E. coliwhole-genome sequencing

𝕏 PostBluesky

MicrobiologyCell ReportsPeer-reviewedNov 1, 2024

Colon cancer and cell transformation by clinical Salmonella strains are associated with bacterial virulence and intracellular fitness

Virginie Stévenin, Claudia E. Coipan, Janneke W. Duijster…·Jacques Neefjes

The paper compares NTS strains associated with colon cancer to controls, finding higher transformation efficiency in case strains linked to gene expression and metabolic traits.

6 citations

humanwhole-genome sequencing

𝕏 PostBluesky