Cell BiologyThe EMBO JournalPeer-reviewed
Activation of goblet cell stress sensor IRE1β is controlled by the mucin chaperone AGR2
Eva Cloots, Phaedra Guilbert, Mathias Provost…·Sophie Janssens
This study identifies AGR2 as a chaperone that regulates IRE1β activity in goblet cells by preventing its dimerization and endonuclease activity.
30 citations