Author

Charles G. Theillet

Centre National de la Recherche ScientifiqueORCID 0000-0001-5555-2759Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Béatrice OrsettiiD· 1 shared Carolina VelázqueziD· 1 shared Céline Lemmers· 1 shared Claude SardetiD· 1 shared Cyril RibeyreiD· 1 shared Ermes CandielloiD· 1 shared Esin OrhaniD· 1 shared Geneviève RodieriD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Béatrice OrsettiORCID

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2 papers

Recent·Most cited

Cancer BiologyCancer ResearchPeer-reviewedJan 29, 2025

Replication poison treated BRCA1-deficient breast cancers are prone to MRE11 over-resection resulting in single strand DNA accumulation and mitotic catastrophe

Imène Tabet, Esin Orhan, Ermes Candiello…·Charles G. Theillet

This study shows BRCA1-deficient breast cancers are highly sensitive to gemcitabine, leading to ssDNA accumulation and mitotic catastrophe, which may enhance antitumor immune response.

3 citations

humanbulk RNA-seq

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Molecular BiologybioRxivPreprintJul 8, 2020

Mitosis without DNA replication in mammalian somatic cells

Olivier Ganier, Malik Lutzmann, Julien Cau…·Marcel Méchali

The paper shows that mammalian somatic cells can enter mitosis without DNA replication, producing haploid daughter cells.

4 citations

humanexperimental assay

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