Author

Esin Orhan

Centre National de la Recherche ScientifiqueORCID 0009-0002-7662-9430Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Béatrice OrsettiiD· 1 shared Carolina VelázqueziD· 1 shared Charles G. TheilletiD· 1 shared Claude SardetiD· 1 shared Cyril RibeyreiD· 1 shared Ermes CandielloiD· 1 shared Geneviève RodieriD· 1 shared Imène TabetiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Béatrice OrsettiORCID

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1 paper

Recent·Most cited

Cancer BiologyCancer ResearchPeer-reviewedJan 29, 2025

Replication poison treated BRCA1-deficient breast cancers are prone to MRE11 over-resection resulting in single strand DNA accumulation and mitotic catastrophe

Imène Tabet, Esin Orhan, Ermes Candiello…·Charles G. Theillet

This study shows BRCA1-deficient breast cancers are highly sensitive to gemcitabine, leading to ssDNA accumulation and mitotic catastrophe, which may enhance antitumor immune response.

3 citations

humanbulk RNA-seq

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