Jean-Philippe Kleman

This study shows dimeric Alix nucleates CHMP4 polymerization, essential for ESCRT-III membrane remodeling, and demonstrates that dimerization is required for plasma membrane repair.

This study shows that LdcI filamentation in E. coli drives peripheral clustering, enhancing acid stress response by spatially organizing the enzyme.

This study combines live cell fluorescence imaging and in situ cryo electron tomography to investigate the septation process in Deinococcus radiodurans, revealing insights into cell envelope architecture and molecular mechanisms of septal growth and closure.

The paper identifies a blue light signaling pathway in green algae that inhibits starch accumulation via PMSK1 dephosphorylation and GAP1 repression.

This study examines stress-induced nucleoid remodeling in D. radiodurans, showing distinct HU protein dynamics under stationary phase and UV-C exposure.

This paper develops a drug-inducible tool to inhibit HIV-1 budding by transiently stabilizing ESCRT-III components, showing varying effects on VLP release.

This paper investigates the acid-stress response of E. coli LdcI using cryo-EM and super-resolution imaging, revealing its supramolecular assembly and proposing a mechanistic model for its function.