Jacob A. Boyer

The paper uses photocatalytic proximity labeling to map HER2 interactions in breast cancer, identifying galectins and PTPRF as key players in resistance and signaling.

This study shows that BRAFV600E mutations inhibit cell migration and invasion through feedback inhibition of RAC1, requiring secondary mutations to overcome this block and enable tumorigenesis.

Dyscovr identifies driver-associated transcriptional changes and prioritizes genes for therapeutic targeting in cancer.

This study shows that senolytic CAR T cells remove senescent cells in the aging gut, improving intestinal regeneration and immune function.