Fernando Vargas

This study identifies fatty acids as regulators of stem-like exhausted CD8 T cells during chronic viral infection, showing their impact on mitochondrial fitness and viral control.

The paper introduces Ion Identity Molecular Networking to connect ion species of the same molecule, improving network connectivity and annotation.

ZODIAC improves molecular formula annotation in metabolomics by combining SIRIUS results with Gibbs sampling, reducing errors and discovering novel compounds.

The paper introduces FBMN, a method for improving molecular networking by enhancing quantitative analysis and isomer distinction using feature detection and alignment tools in the GNPS platform.

The paper develops ReDU, a tool for discovering and re-analyzing metabolomics data in GNPS, following FAIR principles.

This paper expands the interpretability of human metabolomes by using food-based annotations, increasing the fraction of molecular features understood 7-fold.

The paper introduces CycloNovo, a de novo cyclopeptide sequencing algorithm, revealing a vast hidden cyclopeptidome in the human gut and other environments.

The paper describes a workflow for creating MS/MS reference spectra in the GNPS infrastructure, achieving 99.2% accurate annotation of chemical standards.

The paper identifies novel conjugated bile acids produced by the microbiome in mice and humans using mass spectrometry and a murine 3D model.

MASST enables querying of public small-molecule tandem MS data to discover molecular relationships in metabolomics and natural product datasets.

This paper uses untargeted mass spectrometry to analyze chemical changes in foods during preparation and storage, finding that some processes alter molecular composition while others primarily involve extraction.

MetaRiPPquest identifies RiPPs by combining genome/metagenome mining with mass spectrometry analysis, discovering 5 novel natural products from 6 datasets.