Cell BiologyEMBO ReportsPeer-reviewed
Liver sinusoidal endothelial cells constitute a major route for hemoglobin clearance
Gabriela Zurawska, Zuzanna Sas, Aneta Jończy…·Katarzyna Mleczko‐Sanecka
This study identifies liver sinusoidal endothelial cells as the primary cells responsible for hemoglobin clearance, revealing their role in heme detoxification and iron homeostasis through macropinocytosis and the BMP6-hepcidin axis.
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