He Zhang

This study shows that inflammation triggers POLE-mutant colorectal cancer in mice, revealing inflammation as a key driver and establishing a preclinical model for drug discovery.

GEMORNA generates mRNA sequences with enhanced translation capacity and stability, showing significant improvements in expression levels and therapeutic applications.

The paper introduces LazySampling and LinearSampling algorithms for fast RNA secondary structure sampling, achieving linear-time performance and enabling analysis of full-genome RNA structures like SARS-CoV-2.

LinearTurboFold predicts conserved RNA structures for SARS-CoV-2 homologs efficiently, capturing long-range interactions and enabling global structural analysis of full-length genomes.

The paper compiles and analyzes 190 marine invertebrate genomes to explore their diversity, function, and evolutionary relationships.

CoV-Seq provides a webserver and command-line tool for rapid analysis and visualization of SARS-CoV-2 genomes, automatically predicting gene boundaries and identifying variants.

The paper introduces a linear-time machine learning-based RNA folding system that improves accuracy and training speed compared to existing methods.