Author

Yanzhe Wang

Shanghai University of Traditional Chinese MedicineORCID 0000-0001-5983-7196Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Chaoyang YeiD· 2 shared Di HuangiD· 2 shared Ming WuiD· 2 shared Yanfang BaiiD· 2 shared Yufeng XingiD· 2 shared Dong‐Ping CheniD· 1 shared Dongping CheniD· 1 shared Jinghua HuiD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersPathology

Chaoyang YeORCID

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2 papers

Recent·Most cited

PathologybioRxivPreprintOct 8, 2023

Injury induced renal fibrosis promotes cystogenesis and cyst growth in adult mice with autosomal dominant polycystic kidney disease

Ming Wu, Dongping Chen, Yanzhe Wang…·Chaoyang Ye

This study shows that renal fibrosis induced by injury promotes cyst formation and growth in adult ADPKD mice, and targeting EZH2 can reduce fibrosis and cyst growth.

1 citation

mouseexperimental assay

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Molecular BiologybioRxivPreprintNov 3, 2021

Tubular obstruction induced polycystin upregulation is pro-fibrotic and induced a severe cystic phenotype in adult mice with autosomal dominant polycystic kidney disease: the coexistence of polycystin loss and gain function in ADPKD

Ming Wu, Yanzhe Wang, Ying Jing…·Chaoyang Ye

This study shows that upregulation of polycystins in fibrotic kidneys promotes renal fibrosis and cyst growth in ADPKD mice, and that inhibiting polycystins reduces fibrosis and cyst progression.

DOI 10.1101/2021.11.03.467035

mouseexperimental assay

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