Shuvra Shekhar Roy

This paper shows telomere length regulates hTERT expression by modulating TRF2 binding and PRC2-mediated repression, revealing a self-regulatory mechanism in cancer.

The paper inserts G-quadruplex DNA sequences into cells and shows they increase chromatin looping and gene activation over long distances.

This study identifies FDA-approved drugs that bind G-quadruplexes in SARS-CoV-2 genomes, showing significant inhibition of viral replication in hamsters and cell cultures comparable to Remdesivir.

This study evaluates the COVIDSeq protocol for SARS-CoV-2 detection and genetic epidemiology, showing high concordance with RT-PCR and identifying novel variants and lineages.