Mohammad Ali Mohammad Nezhady

The paper develops ALTitude, a machine learning model to predict ALT status from whole genome sequencing data, identifies SMARCAL1 as a therapeutic target in ALT-driven cancers.

This study shows that HCAR1 deficiency in RPE cells causes ER stress and impaired choroidal development, which is reversible with ISRIB treatment.

This study identifies PRMT5's role in promoting EMT in neuroblastoma by regulating EGFR and AKT pathways, leading to NFκB activation and tumor growth.