Vishal C. Kalel

The paper identifies PEX38 as a novel, essential peroxin in Euglenozoa, evolved from a remnant GET-pathway factor, and highlights its role in peroxisomal membrane protein targeting and potential as a therapeutic target.

This study identifies small molecule inhibitors targeting the TbPEX6-TbPEX15 interaction in trypanosomatid parasites, showing trypanocidal activity in vitro.

The paper identifies 28 novel glycosomal membrane proteins in trypanosomes, validates four new ones, and identifies PEX15 as a key protein essential for glycosome biogenesis and parasite survival.

This study identifies an FDA-approved inhibitor that targets glycosome membrane biogenesis in Leishmania parasites, effectively killing them including amastigote forms.

This study identifies TbPEX1 as essential for glycosome biogenesis and trypanosome survival, showing its role in matrix protein import and quality control mechanisms.