Author

Eun Seok Choi

MetroHealth Medical CenterORCID 0000-0001-6073-248XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Osama SweefiD· 2 shared Saori FurutaiD· 2 shared Vandana SharmaiD· 2 shared Veani FernandoiD· 2 shared Xunzhen Zheng· 2 shared Justin SzpendykiD· 1 shared Venetia D. Thomas· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

Osama SweefORCID

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2 papers

Recent·Most cited

Cancer BiologyCancer & MetabolismPeer-reviewedMar 20, 2025

Immunogenic shift of arginine metabolism triggers systemic metabolic and immunological reprogramming to prevent HER2+ breast cancer

Vandana Sharma, Veani Fernando, Xunzhen Zheng…·Saori Furuta

This study shows that long-term SEP treatment prevents HER2+ breast cancer by reprogramming systemic metabolism and immunity, increasing memory T cell formation.

4 citations

mouseproteomics

𝕏 PostBluesky

Cancer BiologyLife Science AlliancePeer-reviewedAug 27, 2024

Reprogramming of breast tumor-associated macrophages with modulation of arginine metabolism

Veani Fernando, Xunzhen Zheng, Vandana Sharma…·Saori Furuta

This study shows that sepiapterin reprograms M2-type tumor-associated macrophages in HER2+ breast tumors to M1-type by modulating arginine metabolism, enhancing immunotherapy response.

27 citations

humanproteomics

𝕏 PostBluesky