Author

Durgadevi Parthasarathy

University of MinnesotaORCID 0000-0001-6105-1192Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Alon HerschhorniD· 2 shared Miranda HarrisiD· 2 shared Dmitriy V. Mazurov· 1 shared Héctor CerveraiD· 1 shared Héctor Cervera-Benet· 1 shared Jeffy Jeffy· 1 shared Joseph SodroskiiD· 1 shared Karunakar Reddy PothulaiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMicrobiology

Alon HerschhornORCID

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2 papers

Recent·Most cited

MicrobiologyNature CommunicationsPeer-reviewedAug 26, 2024

Conformational flexibility of HIV-1 envelope glycoproteins modulates transmitted / founder sensitivity to broadly neutralizing antibodies

Durgadevi Parthasarathy, Karunakar Reddy Pothula, Kim-Marie A. Dam…·Alon Herschhorn

This paper shows that some HIV-1 transmitted/founder Envs are incompletely closed, making them sensitive to antibodies targeting open conformations, and highlights the importance of Env conformational flexibility for bnAb neutralization.

32 citationstop 4%

humanstructural biology

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MicrobiologymBioPeer-reviewedMar 12, 2024

Alternative substitutions of N332 in HIV-1AD8 gp120 differentially affect envelope glycoprotein function and viral sensitivity to broadly neutralizing antibodies targeting the V3-glycan

Jeffy Jeffy, Durgadevi Parthasarathy, Shamim Ahmed…·Alon Herschhorn

This study examines how different amino acids at position 332 of HIV-1AD8 gp120 affect viral sensitivity to antibodies, cold exposure, and infectivity.

14 citations

humanproteomics

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