Author

Cristhian J. Ildefonso

University of Florida HealthORCID 0000-0001-6179-720XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Alfred S. LewiniD· 3 shared Anil P. PateliD· 2 shared Chulbul M. I. Ahmed· 2 shared Michael T. MassengilliD· 2 shared Archana JalligampalaiD· 1 shared Brianna M Tischner· 1 shared Erin Walsh· 1 shared Hong Li· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersNeuroscience

Alfred S. LewinORCID

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3 papers

Recent·Most cited

NeuroscienceScientific ReportsPeer-reviewedAug 17, 2025

Modulation of Retinal Inflammation Delays Degeneration in a Mouse Model of Geographic Atrophy

Raela B Ridley, Brianna M Tischner, Jieun Lee…·Cristhian J. Ildefonso

This study shows that delivering an anti-inflammatory gene via AAV in a mouse model of geographic atrophy delays retinal degeneration and reduces inflammation.

2 citations

mouseexperimental assay

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ImmunologybioRxivPreprintSep 4, 2023

Suppressor of Cytokine Signaling 3 Derived Peptide as a Therapeutic for Inflammatory, and Oxidative Stress Induced Damage to the Retina

Chulbul M. I. Ahmed, Anil P. Patel, Howard M. Johnson…·Alfred S. Lewin

This paper tests a peptide derived from SOCS3 to reduce inflammation and oxidative stress in retinal cells and a mouse model of AMD.

5 citations

humanmouse

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NeuroscienceVision ResearchPeer-reviewedFeb 9, 2023

Binocular Benefit Following Monocular Subretinal AAV Injection in a Mouse Model of Autosomal Dominant Retinitis Pigmentosa (adRP)

Chulbul M. I. Ahmed, Michael T. Massengill, Cristhian J. Ildefonso…·Alfred S. Lewin

This study shows that AAV-RHO820-shRNA820 injection in one eye of adRP mice slows retinal degeneration and preserves function in the untreated contralateral eye.

7 citations

mouseexperimental assay

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